Plant-Based Diet Converts Breast Cancer In Mice From Lethal To Treatable Form

By Katherine Stephen

Researchers at the University of Alabama at Birmingham have found a dietary combination that transforms the most lethal of all breast cancers into a highly treatable breast cancer.

Specifically, scientists involved in the Scientific Reports study say a particular plant-based diet may be the key.

Trygve Tollefsbol, Ph.D., D.O., professor of biology in the College of Arts and Sciences and senior scientist with the Comprehensive Cancer Center as well as Yuanyuan Li, M.D., Ph.D., a research assistant professor of biology, use epigenetics — the study of biological mechanisms that will switch genes on and off — as a mechanism to identify ways we can change human gene expressions in fatal diseases, including breast cancer. All breast cancers are either estrogen receptor-positive or estrogen receptor-negative. The tumors in estrogen receptor, or ER, negative breast cancer are much less likely to respond to hormone therapy than are tumors that are ER-positive, which means that ER-negative breast cancers are typically very aggressive.

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