Researchers Present Findings On Anti-cancer Compounds Discovered At Usa Health Mitchell Cancer Institute

By University of South Alabama

Two new classes of anti-cancer compounds discovered by scientists at USA Health Mitchell Cancer Institute show promise for the treatment or prevention of cancer, researchers told scientists convened for the recent annual meeting of the American Association for Cancer Research in Atlanta.

“Early findings indicate that we are on the right track for developing new anti-cancer drugs that safely and effectively inhibit key oncogenic targets, which are often said to be ‘undruggable,’” said Gary A. Piazza, Ph.D., professor of oncologic sciences and pharmacology and leader of MCI’s Drug Discovery Research Center.

The term “undruggable” describes cancer drivers that are difficult to target with drugs because of their protein structures. Improving the understanding of these oncoproteins was one of 10 recommendations outlined in a 2016 Blue Ribbon Panel Report as part of former Vice President Joe Biden’s National Cancer Moonshot Initiative.Presenting the studies at AACR were Adam B. Keeton, Ph.D., and Bing Zhu, Ph.D., scientists at MCI. The AACR is the world’s oldest and largest professional association of cancer researchers.

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